Liver injury associated with antidepressants
The use of the eHealthMe site and its content is at your own risk. It is based on buspirone hydrochloride the active ingredients of Buspar and Buspar the brand name.
Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk. If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date. Onset of antidepressant-associated hepatotoxicity varies from 5 days to 3 years.
Antidepressant-induced liver injury can occur in the absence of identifiable, underlying risk factors such as cirrhosis and hepatitis infection; only a few cases of hepatic injury involve patients with chronic hepatitis infection.
Some of these cases involve possible drug interactions between antidepressants and concomitant agents that increase the risk for liver injury. BuSpar is slow acting, so it may take a few weeks to feel the effects. Typically, the medication is taken for several months up to a year. When your doctor decides that you should stop taking BuSpar, the dose will gradually be reduced, to help avoid potential effects of withdrawal.
In cases of hypersensitivity, your doctor will discontinue the medication treatment. In addition, as buspirone can affect blood glucose levels , this is problematic for persons with diabetes. Buspar is not recommended for nursing mothers as there is evidence to suggest it may be secreted into breast milk.
Buspirone (Oral Route) Description and Brand Names - Mayo Clinic
I started to get panic attacks just picking my kids off from kindergarten. At first lower dosage didn't help much and mid level dosage just helped a few hours. First tapered down from 30 to 25 to 20mg a day within 3 weeks as per Pdocs orders. Therefore I recommend this medication.
It helps me control my anxiety.
For the most part I feel ok off of it, but my anxiety is really really bad and my body hurts really bad as well.
I did have the dizziness again when I raised the dose but not as bad and it only lasted a few minutes this time. Some panic attacks.
Nobody told this drug could turn against me and do the opposite it should be doing. It was working really good up until June. All of a sudden I started getting very dizzy and lightheaded. I also started having awful heart palpitations when I took the medicine. For the most part I feel ok off of it, but my anxiety is really really bad and my body hurts really bad as well.
They told me that I could stop taking the medicine whenever I wanted, but when I tried to quit cold turkey it really messed me up and I felt like crap.
They are horrible and last weeks. It was terrible! I warn people against this medication and will never take it again! Joyce September 27, , pm What were the withdraw effects you had?
They were only small incidents forgetting to put in a coffee filter when I made a pot of coffee, thinking I had loaded the dishwasher and started it, etc , but it was enough to scare us all. It was like it was making me bipolar. Then I started having panic attacks, which I never had before taking it; I just had generalized anxiety. So I decided to quit taking it suddenly maybe a mistake and got severe withdrawal symptoms — dizziness, nausea, loss of appetite, trembling, hot flashes, severe anxiety.
I went to the ER a couple times it was so bad. Any suggestions? Reply Link Alison September 14, , am My psychiatrist took me off Buspar 10 mg cold turkey a couple weeks ago. I have been taking Buspar for well over 10 years. This last week is the worst I have felt since before being treated initially 17 years ago for panic disorder.
My chest is tight, I feel tingling, dizzy, and just an all over feeling of impending doom. I started myself back on it tonight. Getting off the Buspar is the only thing that has changed. I'm not sure how I will be able to work on Monday. Im on Trazodone gabapentin lyrica and pain mefs. I have anxiety fibromyalgia bulging disc neuropathy migraines and some others i can't think of right now.
Gabapentin and the trazodone seem to help for the anxiety. Hope you will get better too. Did you still get anxiety while taking the buspar?
It's been the first week and I still get anxiety. So scary. Thanks so much for talking to me about this. TR Hello pepper. So how do u take the gabapentin and how much? I did have anxiety for the first 3 week of taking buspar but eventually it went away. Buspar did very well for my anxiety. I hope it works good for you. Just hang in there it does get better. Do you know why that would be or expwrienced this? I would wake up in the middle of the night freaking out cause of anxiety.
I felt like i couldn't breath my chest was tight i couldn't even stand for my clothes to touch my. I felt overwhelmed with emotions. I would cry. It was so bad i wanted to go to the emergency room but thought better of it cause there was nothing they could do. Ya know? I just had to ride it out. I really can stand to feel that way.
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It was actually on 26 Sep ! They are found in some fruits and vegetables, and often used as sweeteners.
This drug has made me so much more outgoing, it's easier to have conversation, I'm not so self conscious, and I just feel better. Subjects receiving buspirone 5 mg b.
The 5 mg and 10 mg tablets are scored so they can be bisected. Accessed July 3,
Scared me to buspar. Nguyen notes. Enzymes your physician if and are pregnant, or if you are planning to become pregnant, or if you become pregnant while you are taking BuSpar. Because animal reproduction studies are not always predictive of human response, this drug should liver used during pregnancy only if clearly needed. I felt terrible on it.
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I felt terrible on it. It also made my voice hoarse also my chest feel weird and I also was very jittery I cannot give this med, 2 to 4 weeks to start working I need something that will work ASAP! Definitely not for me will not be taking this anymore!
My voice has been sore. I did not that can happen. I also have othe side effects. MA Matthew 3 Apr I been on buspar for a year and I don't like the way it makes me feel I told my therapist about how I feel more anxious can't concentrate and can't sleep and he just. BA barryjo 15 Sep My doctor started me on Buspar 10mg twice a day about a month ago.. Almost immediately I experienced headaches.
I didn't associate it with the Buspar at that time. I worked myself up to 10 mg twice a day, and right away I started experiencing small panic attacks. I have had them in the past, but not for 13 years.. I called my doctor and he prescribed xanax. I knew that I could take it from past experience..
I stopped the Buspar and after 72 hours, the panic attacks were gone and I don't need to take the xanax.. To achieve an optimal therapeutic response, at intervals of 2 to 3 days the dosage may be increased 5 mg per day, as needed. The maximum daily dosage should not exceed 60 mg per day. I had a hard time with the twice a day.
So i took both dosages at night. After a week to be moved up to two whole dosages. I cant breath. I feel like im losing control of the way im breathing. My heart palpitations are crazy. Apparently this isn't true for everyone who takes buspirone but please please be cautious of it because if it starts making you feel low, it will only make you lower and lower until you cannot function.
After coming off Buspirone I was feeling myself within a week. Please be careful and be very very cautious of low mood. Then out of nowhere, it made my anxiety 1, times worse. Scared me to death. I still had my panic attacks and made me depressed it was a hit or miss with the medication it worked a couple of times but only for a couple of hours then my anxiety and panic would come right back sometimes even worse then before I also had adhd and it made my adhd worse just horrible..
I was really rooting for the medication I think in my case I need something daily not temporary relief Wich is what buspar offers I upped my dose to 5mg twice a day thinking that it would help my worsening anxiety, but it only made me spiral even more.
I would be paranoid every night that something was out to get me, I had crying fits, I had a nightmare I was being choked in my sleep and woke up choking. This drug literally terrorized me. As soon as I read these reviews I realized it was not just me and went off of it.
I feel so much healthier and happier now. Some panic attacks. Doctor asked me not to take it anymore and I was afraid of withdrawal so I researched Buspar. The only thing is I get a little dizzy but only for a half hour. No other side effects.
The only thing I don't like is the side effect of twitching for about 30 mins after taking. Just like all anxiety meds, if you stop taking it without dosing down, it can or will make your anxiety worst. Read the warning label. But this works great for me! I was asked to take it twice a day but I decided its best to take before bed because after I take it I will fall asleep in the next two hours, theres no fighting it. But It works well for me.
It helps me control my anxiety. I have adhd so my anxiety is very hyperactive, and Buspar helps slow my thoughts down enough to where I can think clearly. And it helps me sleep at night.